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IMAT Microbiome discovery platform

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  • IMAT Microbiome discovery platform

    description: A precision microfluidic instrument engineered to sustain stable cultures of microbial communities and gut cells — unlocking bi-directional signaling and physiological relevant experiments. A proprietary gut-on-a-chip platform designed to assess the impac
    Summarize
    A precision microfluidic instrument engineered to sustain stable cultures of microbial communities and gut cells — unlocking bi-directional signaling and physiological relevant experiments. A proprietary gut-on-a-chip platform designed to assess the impact of nutrition products on the gut microbiome and metabolic health.
    Co-Culture
    Stable co-culture of human cells and microbes
    Automation
    Automated microfluidic control enabling reproducible parallel experiments
    Bioinformatics
    Integrated data and analysis platform enabling microbiome insights and discovery

    Advantage:
    Microbiota cultures
    Stable microbial cultures under controlled conditions
    Automation
    Automated microfluidic control enabling reproducible parallel experiments
    Bioinformatics
    Integrated data and analysis platform enabling microbiome insights and discovery
    Biohub
    We turn complex microbiome data into actionable intelligence, learning from every project to build a proprietary knowledge base

    Key feature:

    MV-Reactor
    High-Throughput Microbial Screening
    The MV-Reactor cartridge is designed for fast, cost-efficient in vitro screening of microbial communities and compounds under gut-like conditions.
    Single-chamber design for high-throughput experiments
    Maintains strict anaerobic or aerobic environments
    Ideal for testing probiotics, postbiotics, and antimicrobials
    Compatible with human, animal, and synthetic microbiota
    Optimised for faecal fermentation studies

    microGUT
    A Multi-Stage Gut-On-Chip Cartridge
    microGUT is a modular, multi-compartment cartridge that mimics the entire human colon and small intestine, providing a dynamic, spatially resolved simulation of the gut.
    Models 4 gut regions (SI, AC, TC, DC) with independent control of flow and pH
    Spiral chambers for realistic nutrient gradients and retention time
    Plug-and-play with the IMAT automation core
    Supports complex, long-term microbial colonisation

    Co-culture
    Microbiome & Host Cell Interactions
    Our Co-Culture Module enables direct interaction studies between live microbial ecosystems and human gut epithelial cells, advancing the frontier of in vitro human models.
    Two-chamber system with a semipermeable membrane interface
    Maintains differential oxygen and nutrient gradients
    Mimics the mucosal interface of the human gut
    Enables measurement of host responses (e.g., cytokines, barrier integrity)
    Application:
    Microbiome screening pipelines
    Batch testing for product development
    Safety and efficacy profiling of novel ingredients
    Studying microbiome-host-diet interactions
    Mapping drug and nutrient metabolism across the gut
    Understanding microbial succession and functional shifts
    Comparing different diets or treatment regimes in a time-resolved setup
    Gut barrier and inflammation studies
    Microbial metabolite-host cross-talk
    Preclinical screening of therapeutics and functional foods
    Immune and metabolic response assays
    Detailed Specifications
    Specification:
    Data Sequencing
    Amplicon (16S, ITS), or RAW files and let us handle the analysis workflow
    Data Analysis
    Transform data into meaningful microbiome insights to improve discovery, directly and beyond
    Knowledge Hub
    Deploy an ever-growing hub of microbiome research, references, and emerging insights
    Sequencing data
    Amplicon 16S, ITS
    Shotgun metagenomics (Illumina NGS)
    Metabolomics (optional/on-demand)
    Bioinformatics processing
    Quality check
    Taxonomy profiling
    Functional profiling
    Custom analysis (on-demand)
    Downstream analysis
    Statistical analysis
    Ecological metrics
    Custom analysis (on-demand)